c:\ian\git\artbin\package\artbin.ado
*!version 2.1.0 IW     04jan2024
c:\ian\git\artbin\package\art2bin.ado
*!version 1.01  09june2022

ART - ANALYSIS OF RESOURCES FOR TRIALS (binary version 2.1.0 04jan2024)
------------------------------------------------------------------------------
A sample size program by Abdel Babiker, Patrick Royston, Friederike Barthel, 
Ella Marley-Zagar and Ian White
MRC Clinical Trials Unit at UCL, London WC1V 6LJ, UK.
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Type of trial                          superiority
Number of groups                       2
Favourable/unfavourable outcome        favourable
                                       Inferred by the program
Allocation ratio                       equal group sizes
Statistical test assumed               unconditional comparison of 2
                                        binomial proportions
                                        using the wald test
Local or distant                       distant
Continuity correction                  no

Anticipated event probabilities        0.050  0.100 

Alpha                                  0.050 (two-sided)
                                        (taken as .025 one-sided)
Power (designed)                       0.900

Total sample size (calculated)         1156

Sample size per group (calculated)     578 578
Expected total number of events        86.7
Expected number of events per group    28.9 57.8
------------------------------------------------------------------------------

ART - ANALYSIS OF RESOURCES FOR TRIALS (binary version 2.1.0 04jan2024)
------------------------------------------------------------------------------
A sample size program by Abdel Babiker, Patrick Royston, Friederike Barthel, 
Ella Marley-Zagar and Ian White
MRC Clinical Trials Unit at UCL, London WC1V 6LJ, UK.
------------------------------------------------------------------------------
Type of trial                          superiority
Number of groups                       2
Favourable/unfavourable outcome        favourable
                                       Inferred by the program
Allocation ratio                       equal group sizes
Statistical test assumed               unconditional comparison of 2
                                        binomial proportions
                                        using the wald test
Local or distant                       distant
Continuity correction                  no

Anticipated event probabilities        0.100  0.200 

Alpha                                  0.100 (two-sided)
                                        (taken as .05 one-sided)
Power (designed)                       0.800

Total sample size (calculated)         310

Sample size per group (calculated)     155 155
Expected total number of events        46.5
Expected number of events per group    15.5 31
------------------------------------------------------------------------------

ART - ANALYSIS OF RESOURCES FOR TRIALS (binary version 2.1.0 04jan2024)
------------------------------------------------------------------------------
A sample size program by Abdel Babiker, Patrick Royston, Friederike Barthel, 
Ella Marley-Zagar and Ian White
MRC Clinical Trials Unit at UCL, London WC1V 6LJ, UK.
------------------------------------------------------------------------------
Type of trial                          superiority
Number of groups                       2
Favourable/unfavourable outcome        favourable
                                       Inferred by the program
Allocation ratio                       equal group sizes
Statistical test assumed               unconditional comparison of 2
                                        binomial proportions
                                        using the wald test
Local or distant                       distant
Continuity correction                  no

Anticipated event probabilities        0.050  0.100 

Alpha                                  0.050 (two-sided)
                                        (taken as .025 one-sided)
Power (calculated)                     0.900

Total sample size (designed)           1156

Sample size per group (designed)       578 578
Expected total number of events        86.7
Expected number of events per group    28.9 57.8
------------------------------------------------------------------------------

ART - ANALYSIS OF RESOURCES FOR TRIALS (binary version 2.1.0 04jan2024)
------------------------------------------------------------------------------
A sample size program by Abdel Babiker, Patrick Royston, Friederike Barthel, 
Ella Marley-Zagar and Ian White
MRC Clinical Trials Unit at UCL, London WC1V 6LJ, UK.
------------------------------------------------------------------------------
Type of trial                          superiority
Number of groups                       2
Favourable/unfavourable outcome        favourable
                                       Inferred by the program
Allocation ratio                       equal group sizes
Statistical test assumed               unconditional comparison of 2
                                        binomial proportions
                                        using the wald test
Local or distant                       distant
Continuity correction                  no

Anticipated event probabilities        0.100  0.200 

Alpha                                  0.100 (two-sided)
                                        (taken as .05 one-sided)
Power (calculated)                     0.801

Total sample size (designed)           310

Sample size per group (designed)       155 155
Expected total number of events        46.5
Expected number of events per group    15.5 31
------------------------------------------------------------------------------

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*** ARTBIN HAS PASSED ALL SOFTWARE TESTING POINT 2 **********
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