*! version 1.0.0 02jan2023

Title

ascvd -- Computes ACC/AHA 10-year risk for an initial hard atherosclerotic cardiovascular disease (ASCVD) event

Syntax

ascvd using data in memory

ascvd
[if] [in]
,
female(varname)
black(varname)
age(varname)
chol(varname)
hdl(varname)
sbp(varname)
trhtn(varname)
smoker(varname)
diabetes(varname)
[ include ]

Immediate form of ascvd

ascvdi
,
female(0/1)
black(0/1)
age(#)
chol(#)
hdl(#)
sbp(#)
trhtn(0/1)
smoker(0/1)
diabetes(0/1)
[ include ]

ascvd options

Required
female(varname) gender, where female = 1 and male = 0

black(varname) race, where black = 1 and all others = 0

age(varname) age in years

chol(varname) total cholesterol level (mg/dL)

hdl(varname) high density lipoprotein level (mg/dL)

sbp(varname) systolic blood pressure (mmHg)

trhtn(varname) treated for hypertension, where treated = 1 and not treated = 0

smoker(varname) smoking status, where smoker = 1 and non-smoker = 0

diabetes(varname) diabetes status, where diabetic = 1 and non-diabetic = 0

Optional
include produces indicator for whether patient's input values meet ACC/AHA guidelines for computing ASCVD risk

immediate options

Required
female(#) gender, where female = 1 and male = 0

black(#) race, where black = 1 and all others = 0

age(#) age in years

chol(#) total cholesterol level (mg/dL)

hdl(#) high density lipoprotein level (mg/dL)

sbp(#) systolic blood pressure (mmHg)

trhtn(#) treated for hypertension, where treated = 1 and not treated = 0

smoker(#) smoking status, where smoker = 1 and non-smoker = 0

diabetes(#) diabetes status, where diabetic = 1 and non-diabetic = 0

Optional
include indicates whether patient's input values meet ACC/AHA guidelines for computing ASCVD risk

Description

ascvd Computes 10-year risk for an initial hard atherosclerotic cardiovascular disease (ASCVD) event (defined as first occurrence
of non-fatal myocardial infarction, congestive heart disease death, or fatal or nonfatal stroke), based on American College of
Cardiology/American Heart Association (ACC/AHA) guidelines (Goff et al. 2014).

ascvdi is the immediate form of ascvd; see immed.

Remarks

The ASCVD risk models were generated primarily for African American and White women and men. However, the number of African Americans,
particularly men, used in generating these models was relatively low, creating a somewhat greater level of uncertainty with respect to these estimates. The
absence of other ethnicities limits the applicability of the equations to other populations, in particular to lower risk populations, such as Asians or
Hispanics/Latinos. Application of the Pooled Cohort Equations to these and other patient subgroups should be performed with caution, as it may lead to
unpredictable over- and underestimation in these and other patient subgroups.

The ASCVD risk models are also limited in their accuracy for individuals with characteristics outside of the ranges in which the models were generated and tested
(or meet ACC/AHA guidelines for computing the risk score). ascvd will compute the risk score, regardless of whether the input values are within acceptable
ranges or not. The include option will tell the user whether an individual input values are with acceptable ranges or not. More specifically: age between 40 and 79;
total cholesterol between 130 and 320; high density lipoprotein between 20 and 100; and systolic blood pressure between 90 and 200.

Examples

Setup

. use "example_ascvd.dta", clear

Run ascvd using data in memory

. ascvd , age(age) female(female) black(black) chol(chol) hdl(hdl) sbp(sbp) trhtn(bptreat) smoker(smoke) diabetes(diabetes)

Rerun command, specifying the "include" option to indicate whether patients' input values meet ACC/AHA guidelines for computing ASCVD risk

. ascvd , age(age) female(female) black(black) chol(chol) hdl(hdl) sbp(sbp) trhtn(bptreat) smoker(smoke) diabetes( diabetes) include

Run ascvdi for an individual case and specify the include option

. ascvdi , age(58) female(1) black(0) chol(270) hdl(99) sbp(190) trhtn(1) smoker(0) diabetes(1) include

Stored results

ascvdi stores the following in r():

Scalars

r(ascvd10) 10-year risk estimate

References

Goff Jr, D.C., Lloyd-Jones, D.M., Bennett, G., Coady, S., D'agostino, R.B., Gibbons, R., Greenland, P., Lackland, D.T.,
Levy, D., O'donnell, C.J. and J.G. Robinson. 2014. 2013 ACC/AHA guideline on the assessment of cardiovascular risk:
a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.
Circulation 129(25_suppl_2), S49-S73.

see also: "https://www.cvriskcalculator.com/"

Citation of ascvd

ascvd is not an official Stata command. It is a free contribution
to the research community, like a paper. Please cite it as such:

Linden, Ariel (2023). ASCVD: Stata module for computing ACC/AHA 10-year risk for an initial hard atherosclerotic cardiovascular disease (ASCVD) event

Author

Ariel Linden

President, Linden Consulting Group, LLC

alinden@lindenconsulting.org

http://www.lindenconsulting.org

Acknowledgments

I would like to thank Albert Botchway for advocating that I write this package.

Also see

framingham (if installed)