Title

drmeta_gof -- Goodness-of-fit after dose-response meta-analysis

Syntax for predict

drmeta_gof [ , r2s opvdplot(dosevar, [xb|xbs|fitted]) drvdplot(dosevar) dovpplot twoway_options ]

Description

The drmeta_gof command provides tools (deviance test, R-squared)
to evaluate the goodness-of-fit in dose-response meta-analysis.
It is a post-estimation tool of the drmeta command.

Options

r2s shows study-specific coefficient of determination (R-squared).

opvdplot(dosevar, [xb|xbs|fitted]) plots the observed and specified predicted values vs the specified dose.
The default is to use study-specific predictions using generalized least squares (xbs).
See drmeta_predict.

drvdplot(dosevar) plots the decorrelated residuals vs the specified dose.

dovpplot plots decorrelated observed contrasts vs predicted contrasts.

Examples

* Read data from 7 simulated studies with a common underlying linear dose-response relationship.
* The true value of the slope is 0.1 (RR=1.11).

use http://www.stats4life.se/data/table1sim.dta, clear

* One-stage random-effects dose-response model assuming a linear trend

drmeta logor dose , se(selogor) data(n case) id(id) type(study) reml
drmeta_gof
drmeta_gof, r2s
drmeta_gof, opvd(dose)
drmeta_gof, opvd(dose, fitted)
drmeta_gof, dovp

* One-stage random-effects dose-response model using restricted cubic splines

mkspline doses = dose, nk(3) cubic
drmeta logor doses1 doses2 , se(selogor) data(n case) id(id) type(study) reml
drmeta_gof, r2s
drmeta_gof, drvd(dose)
drmeta_gof, opvd(dose)
drmeta_gof, dovp

Reference

Discacciati A, Crippa A, Orsini N. Goodness of fit tools for dose-response meta-analysis of binary outcomes. Research Synthesis Methods. 2017 Jun;8(2):149-160.

Author

Nicola Orsini, Biostatistics Team,
Department of Public Health Sciences, Karolinska Institutet, Sweden

Support

http://www.stats4life.se

nicola.orsini@ki.se

Help: drmeta