{smcl} {* *! version 1.0 14 May 2018}{...} {vieweralsosee "" "--"}{...} {vieweralsosee "Install command2" "ssc install command2"}{...} {vieweralsosee "Help command2 (if installed)" "help command2"}{...} {viewerjumpto "Syntax" "est_fixed##syntax"}{...} {viewerjumpto "Description" "est_fixed##description"}{...} {viewerjumpto "Options" "est_fixed##options"}{...} {viewerjumpto "Remarks" "est_fixed##remarks"}{...} {viewerjumpto "Examples" "est_fixed##examples"}{...} {title:Title} {phang} {bf:est_fixed} {hline 2} Determine point estimates in a single-stage single-arm trial design for a single binary endpoint {marker syntax}{...} {title:Syntax} {p 8 17 2} {cmdab:est_fixed} [{cmd:,} {it:options}] {synoptset 20 tabbed}{...} {synopthdr} {synoptline} {syntab:Main} {synopt:{opt n(#)}} Sample size of the considered design. Defaults to 25.{p_end} {synopt:{opt pi(numlist)}} Numlist of response probabilities to evaluate the expected performance of the point estimation procedures at. This will internally default to 0,0.01,...,1.{p_end} {synopt:{opt sum:mary(#)}} An integer indicating whether a summary of the function's progress should be printed (summary = 1) to the console. Defaults to 0.{p_end} {synopt:{opt pl:ot}} Indicates that the RMSE curve of the estimation procedure should be plotted.{p_end} {synopt:{opt *}} Additional options to use during plotting.{p_end} {synoptline} {p2colreset}{...} {p 4 6 2} {marker description}{...} {title:Description} {pstd} Determines all possible point estimates (the MLEs) at the end of a single-stage single-arm trial for a single binary endpoint, as determined using des_fixed. In addition, the performance of the point estimation procedure (including its expected value, bias, and variance) for each value of pi in the supplied numlist pi, will also be evaluated. {marker options}{...} {title:Options} {dlgtab:Main} {phang} {opt n(#)} Sample size of the considered design. Defaults to 25. {phang} {opt pi(numlist)} Numlist of response probabilities to evaluate the expected performance of the point estimation procedures at. This will internally default to 0,0.01,...,1. {phang} {opt sum:mary(#)} An integer indicating whether a summary of the function's progress should be printed (summary = 1) to the console. Defaults to 0. {phang} {opt pl:ot} Indicates that the RMSE curve of the estimation procedure should be plotted. {phang} {opt *} Additional options to use during plotting. {marker examples}{...} {title:Examples} {phang} {stata est_fixed} {phang} {stata est_fixed, n(30)} {title:Author} {p} Michael J. Grayling, MRC Biostatistics Unit, Cambridge. Email {browse "mjg211@cam.ac.uk":mjg211@cam.ac.uk} {title:See Also} Related commands: {help des_fixed} (if installed) {help opchar_fixed} (if installed) {help ci_fixed} (if installed) {help pval_fixed} (if installed)